18-(tert-Butoxy)-18-oxooctadecanoic acid (CAS 843666-40-0)

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18-(tert-Butoxy)-18-oxooctadecanoic acid

CAS No. 843666-40-0
18-(tert-Butoxy)-18-oxooctadecanoic acid structure
Chemical structure
CAS No.843666-40-0
SynonymsOctadecanedioic acid mono-tert-butyl ester; C18 diacid mono-Bu ester; fatty acyl chain precursor
CategoryPharmaceutical Intermediates / Peptides & linkers
Assay / Purity97%
Molecular FormulaC22H42O4
Molecular Weight370.57
Melting Point—
Boiling Point—
Density—
Flash PointNot applicable (solid)
AppearanceWhite to off-white powder

Application and positioning

Mono-protected C18 diacid used to build the fatty-acyl side chain of acylated GLP-1 analogues — the hydrophobic anchor that extends dosing intervals. Supplied at high purity with tight control on the diacid and diester impurities; suitable for scale-up conjugation routes. Laurand supplies it from audited Chinese producers in kilogram to multi-hundred-kilogram lots; process and regulatory documentation is coordinated case by case with the manufacturing site.

Quality and documentation

  • Batch-specific Certificate of Analysis with HPLC purity and a full impurity profile
  • Chiral purity by chiral HPLC where the molecule carries defined stereocentres
  • Residual solvent data against ICH Q3C and elemental impurity data against ICH Q3D on request
  • Structure confirmation by NMR and MS on first shipments
  • SDS in the language of your market, with GHS classification for the destination

Packaging and handling

  • 1 kg, 5 kg and 25 kg fibre drums with inner PE liner; amber glass bottles for gram quantities
  • Sealed, dry and protected from light; cold-chain arrangement discussed per product where the intermediate requires it
  • Store at ambient temperature in a dry warehouse, away from oxidising agents and moisture

Related products

Values marked (predicted) are calculated estimates; the rest are published literature or supplier data. Where a property has no published value we leave it blank rather than estimate it. The specification of the delivered lot is confirmed with the quotation.

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Reference: CAS 843666-40-0 · PubChem CID 27282473