Fmoc-D-tryptophan (CAS 86123-11-7)

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Fmoc-D-tryptophan

CAS No. 86123-11-7
Fmoc-D-tryptophan structure
Chemical structure
CAS No.86123-11-7
SynonymsFmoc-D-Trp-OH; N-Fmoc-D-tryptophan; (R)-2-Fmoc-amino-3-(indol-3-yl)propionic acid
CategoryPharmaceutical Intermediates / Peptides & linkers
Assay / Purity98%
Molecular FormulaC26H22N2O4
Molecular Weight426.47
Melting Point—
Boiling Point—
Density—
Flash PointNot applicable (solid)
AppearanceWhite to off-white powder

Application and positioning

The D-tryptophan residue of octreotide — the unnatural configuration that locks the somatostatin pharmacophore into its stable beta-turn conformation. Fmoc-protected for SPPS; D/L isomer ratio verified by chiral HPLC on every batch. Laurand supplies it from audited Chinese producers in kilogram to multi-hundred-kilogram lots; process and regulatory documentation is coordinated case by case with the manufacturing site.

Quality and documentation

  • Batch-specific Certificate of Analysis with HPLC purity and a full impurity profile
  • Chiral purity by chiral HPLC where the molecule carries defined stereocentres
  • Residual solvent data against ICH Q3C and elemental impurity data against ICH Q3D on request
  • Structure confirmation by NMR and MS on first shipments
  • SDS in the language of your market, with GHS classification for the destination

Packaging and handling

  • 1 kg, 5 kg and 25 kg fibre drums with inner PE liner; amber glass bottles for gram quantities
  • Sealed, dry and protected from light; cold-chain arrangement discussed per product where the intermediate requires it
  • Store at ambient temperature in a dry warehouse, away from oxidising agents and moisture

Related products

Values marked (predicted) are calculated estimates; the rest are published literature or supplier data. Where a property has no published value we leave it blank rather than estimate it. The specification of the delivered lot is confirmed with the quotation.

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Reference: CAS 86123-11-7 · PubChem CID 978344