Ruxolitinib Phosphate (CAS 1092939-17-7)
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Ruxolitinib Phosphate
CAS No. 1092939-17-7
磷酸芦可替尼

Chemical structure
| CAS No. | 1092939-17-7 |
|---|---|
| Synonyms | INCB 018424; (betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile phosphate |
| Category | Anti-Cancer API / Anti-Cancer |
| Assay / Purity | 99% |
| Molecular Formula | C17H21N6O4P |
| Molecular Weight | 404.4 |
| Melting Point | — |
| Boiling Point | — |
| Density | — |
| Flash Point | — |
| Appearance | White to off-white or light pink solid powder |
Application and positioning
Ruxolitinib phosphate is a selective JAK1/JAK2 inhibitor that suppresses JAK-STAT signalling, supplied as the phosphate salt. It is used in oral tablets for myelofibrosis, polycythaemia vera and steroid-refractory graft-versus-host disease. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.
Quality and documentation
- Batch-specific Certificate of Analysis issued by the manufacturing site
- SDS/MSDS and specification sheet available on request
- Residual solvents and elemental impurities statements discussed per project
- For pharmaceutical manufacturing and R&D use only — not for direct administration
Packaging and handling
- Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
- Small quantities in sealed aluminium foil bags
- Palletised for air and sea freight; store dry, ventilated and protected from light
Related products
- Vandetanib (CAS 443913-73-3)
- Veliparib (CAS 912444-00-9)
- Veliparib dihydrochloride (CAS 912445-05-7)
- Vemurafenib (CAS 918504-65-1)
- 4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine (CAS 941685-27-4)
- 3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile (CAS 1153949-38-2)
Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.
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Request a QuoteReference: CAS 1092939-17-7 · PubChem CID 25127112