Ruxolitinib Phosphate (CAS 1092939-17-7)

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Ruxolitinib Phosphate

CAS No. 1092939-17-7
磷酸芦可替尼
Ruxolitinib Phosphate structure
Chemical structure
CAS No.1092939-17-7
SynonymsINCB 018424; (betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile phosphate
CategoryAnti-Cancer API / Anti-Cancer
Assay / Purity99%
Molecular FormulaC17H21N6O4P
Molecular Weight404.4
Melting Point—
Boiling Point—
Density—
Flash Point—
AppearanceWhite to off-white or light pink solid powder

Application and positioning

Ruxolitinib phosphate is a selective JAK1/JAK2 inhibitor that suppresses JAK-STAT signalling, supplied as the phosphate salt. It is used in oral tablets for myelofibrosis, polycythaemia vera and steroid-refractory graft-versus-host disease. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.

Quality and documentation

  • Batch-specific Certificate of Analysis issued by the manufacturing site
  • SDS/MSDS and specification sheet available on request
  • Residual solvents and elemental impurities statements discussed per project
  • For pharmaceutical manufacturing and R&D use only — not for direct administration

Packaging and handling

  • Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
  • Small quantities in sealed aluminium foil bags
  • Palletised for air and sea freight; store dry, ventilated and protected from light

Related products

Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.

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Reference: CAS 1092939-17-7 · PubChem CID 25127112