Temozolomide (CAS 85622-93-1)

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Temozolomide

CAS No. 85622-93-1
替莫唑胺
Temozolomide structure
Chemical structure
CAS No.85622-93-1
Synonyms4-Methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide
CategoryAnti-Cancer API / Anti-Cancer
Assay / Purity99%
Molecular FormulaC6H6N6O2
Molecular Weight194.15
Melting Point—
Boiling Point—
Density—
Flash Point—
AppearanceWhite or light pink solid powder

Application and positioning

Temozolomide is an oral imidazotetrazine prodrug that converts to the methylating agent MTIC and alkylates DNA at O6-guanine. It is used in oral capsules for glioblastoma multiforme and anaplastic astrocytoma, and is part of standard concomitant chemoradiation. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.

Quality and documentation

  • Batch-specific Certificate of Analysis issued by the manufacturing site
  • SDS/MSDS and specification sheet available on request
  • Residual solvents and elemental impurities statements discussed per project
  • For pharmaceutical manufacturing and R&D use only — not for direct administration

Packaging and handling

  • Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
  • Small quantities in sealed aluminium foil bags
  • Palletised for air and sea freight; store dry, ventilated and protected from light

Related products

Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.

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Reference: CAS 85622-93-1 · PubChem CID 5394