(2S,5R)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide (CAS 1192651-49-2)

Application and positioning

The bicyclic 1,6-diazabicyclo[3.2.1]octane core of avibactam-type β-lactamase inhibitors, with the N-6 oxygen carried as the benzyl ether. The active configuration is (2S,5R), so enantiomeric purity is the specification that decides whether the batch is usable. Laurand supplies it from audited Chinese producers in kilogram to multi-hundred-kilogram lots; process and regulatory documentation is coordinated case by case with the manufacturing site.

Quality and documentation

• Batch-specific Certificate of Analysis with HPLC purity and a full impurity profile
• Chiral purity by chiral HPLC where the molecule carries defined stereocentres
• Residual solvent data against ICH Q3C and elemental impurity data against ICH Q3D on request
• Structure confirmation by NMR and MS on first shipments
• SDS in the language of your market, with GHS classification for the destination

Packaging and handling

• 1 kg, 5 kg and 25 kg fibre drums with inner PE liner; amber glass bottles for gram quantities
• Sealed, dry and protected from light; cold-chain arrangement discussed per product where the intermediate requires it
• Store at ambient temperature in a dry warehouse, away from oxidising agents and moisture

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Values marked (predicted) are calculated estimates; the rest are published literature or supplier data. Where a property has no published value we leave it blank rather than estimate it. The specification of the delivered lot is confirmed with the quotation.