4'-(Bromomethyl)-2-cyanobiphenyl (CAS 114772-54-2)

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4′-(Bromomethyl)-2-cyanobiphenyl

CAS No. 114772-54-2
4'-(Bromomethyl)-2-cyanobiphenyl structure
Chemical structure
CAS No.114772-54-2
Synonyms4′-(Bromomethyl)[1,1′-biphenyl]-2-carbonitrile
CategoryPharmaceutical Intermediates / Cardiovascular
Assay / Purity99%
Molecular FormulaC14H10BrN
Molecular Weight272.14
Melting Point—
Boiling Point—
Density—
Flash PointNot applicable (solid)
AppearanceWhite to off-white powder

Application and positioning

The benzylation partner that installs the biphenylmethyl side chain in sartan synthesis — the step that builds the pharmacophore shared by losartan, valsartan and irbesartan. Moisture-protected packaging for this benzyl bromide; COA with full impurity profile on every batch. Laurand supplies it from audited Chinese producers in kilogram to multi-hundred-kilogram lots; process and regulatory documentation is coordinated case by case with the manufacturing site.

Quality and documentation

  • Batch-specific Certificate of Analysis with HPLC purity and a full impurity profile
  • Chiral purity by chiral HPLC where the molecule carries defined stereocentres
  • Residual solvent data against ICH Q3C and elemental impurity data against ICH Q3D on request
  • Structure confirmation by NMR and MS on first shipments
  • SDS in the language of your market, with GHS classification for the destination

Packaging and handling

  • 1 kg, 5 kg and 25 kg fibre drums with inner PE liner; amber glass bottles for gram quantities
  • Sealed, dry and protected from light; cold-chain arrangement discussed per product where the intermediate requires it
  • Store at ambient temperature in a dry warehouse, away from oxidising agents and moisture

Related products

Values marked (predicted) are calculated estimates; the rest are published literature or supplier data. Where a property has no published value we leave it blank rather than estimate it. The specification of the delivered lot is confirmed with the quotation.

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Reference: CAS 114772-54-2 · PubChem CID 1501912