Cabozantinib Malate (CAS 1140909-48-3)

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Cabozantinib Malate

CAS No. 1140909-48-3
苹果酸卡博替尼
Cabozantinib Malate structure
Chemical structure
CAS No.1140909-48-3
Synonyms(2S)-2-Hydroxybutanedioic acid compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)
CategoryAnti-Cancer API / Anti-Cancer
Assay / Purity99%
Molecular FormulaC32H30FN3O10
Molecular Weight635.6
Melting Point—
Boiling Point—
Density—
Flash Point—
AppearanceOff-white to white solid powder

Application and positioning

Cabozantinib malate is a multi-kinase inhibitor of MET, VEGFR2, AXL and RET, supplied as the malate salt. It is used in oral tablets and capsules for advanced renal cell carcinoma, hepatocellular carcinoma and medullary thyroid cancer. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.

Quality and documentation

  • Batch-specific Certificate of Analysis issued by the manufacturing site
  • SDS/MSDS and specification sheet available on request
  • Residual solvents and elemental impurities statements discussed per project
  • For pharmaceutical manufacturing and R&D use only — not for direct administration

Packaging and handling

  • Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
  • Small quantities in sealed aluminium foil bags
  • Palletised for air and sea freight; store dry, ventilated and protected from light

Related products

Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.

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Reference: CAS 1140909-48-3 · PubChem CID 25102846