Larotrectinib Sulfate (CAS 1223405-08-0)
« Back to Anti-Cancer API
Larotrectinib Sulfate
CAS No. 1223405-08-0
硫酸拉罗替尼
Chemical structure
| CAS No. | 1223405-08-0 |
|---|---|
| Synonyms | (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide sulfate; LOXO-101 |
| Category | Anti-Cancer API / Anti-Cancer |
| Assay / Purity | 99% |
| Molecular Formula | C21H24F2N6O6S |
| Molecular Weight | 526.5 |
| Melting Point | — |
| Boiling Point | — |
| Density | — |
| Flash Point | — |
| Appearance | Off-white to white solid powder |
Application and positioning
Larotrectinib sulfate is a selective inhibitor of the TRK kinases TRKA, TRKB and TRKC, supplied as the sulfate salt. It is used in oral capsules and oral solution for solid tumours harbouring an NTRK gene fusion, irrespective of tumour origin. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.
Quality and documentation
- Batch-specific Certificate of Analysis issued by the manufacturing site
- SDS/MSDS and specification sheet available on request
- Residual solvents and elemental impurities statements discussed per project
- For pharmaceutical manufacturing and R&D use only — not for direct administration
Packaging and handling
- Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
- Small quantities in sealed aluminium foil bags
- Palletised for air and sea freight; store dry, ventilated and protected from light
Related products
- Lorlatinib (CAS 1454846-35-5)
- Neratinib Maleate (CAS 915942-22-2)
- Nintedanib Ethanesulfonate (CAS 656247-18-6)
- Niraparib (CAS 1038915-60-4)
Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.
Interested in this product?
Contact us for price, COA, MSDS and lead time — custom synthesis available.
Request a QuoteReference: CAS 1223405-08-0 · PubChem CID 67330085