Neratinib Maleate (CAS 915942-22-2)
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Neratinib Maleate
CAS No. 915942-22-2
马来酸奈拉替尼
Chemical structure
| CAS No. | 915942-22-2 |
|---|---|
| Synonyms | (E)-N-[4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide maleate |
| Category | Anti-Cancer API / Anti-Cancer |
| Assay / Purity | 99% |
| Molecular Formula | C34H33ClN6O7 |
| Molecular Weight | 673.1 |
| Melting Point | — |
| Boiling Point | — |
| Density | — |
| Flash Point | — |
| Appearance | Yellow to off-white solid powder |
Application and positioning
Neratinib maleate is an irreversible pan-HER tyrosine kinase inhibitor of EGFR, HER2 and HER4, supplied as the maleate salt. It is used in oral tablets for extended adjuvant treatment of early-stage HER2-positive breast cancer. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.
Quality and documentation
- Batch-specific Certificate of Analysis issued by the manufacturing site
- SDS/MSDS and specification sheet available on request
- Residual solvents and elemental impurities statements discussed per project
- For pharmaceutical manufacturing and R&D use only — not for direct administration
Packaging and handling
- Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
- Small quantities in sealed aluminium foil bags
- Palletised for air and sea freight; store dry, ventilated and protected from light
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Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.
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Request a QuoteReference: CAS 915942-22-2 · PubChem CID 67307512