Niraparib (CAS 1038915-60-4)
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Niraparib
CAS No. 1038915-60-4
尼拉帕利
Chemical structure
| CAS No. | 1038915-60-4 |
|---|---|
| Synonyms | (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide; MK-4827,(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide; Niraparib; 2-[4-((3S)-3-Piperidinyl)phenyl]-2H-indazole-7-carboxamide |
| Category | Anti-Cancer API / Anti-Cancer |
| Assay / Purity | 99% |
| Molecular Formula | C19H20N4O |
| Molecular Weight | 320.4 |
| Melting Point | — |
| Boiling Point | — |
| Density | — |
| Flash Point | — |
| Appearance | — |
Application and positioning
Niraparib is an oral inhibitor of PARP-1 and PARP-2 that induces synthetic lethality in cells with homologous recombination deficiency. It is used in capsules and tablets as maintenance therapy for advanced ovarian, fallopian tube and primary peritoneal cancer. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.
Quality and documentation
- Batch-specific Certificate of Analysis issued by the manufacturing site
- SDS/MSDS and specification sheet available on request
- Residual solvents and elemental impurities statements discussed per project
- For pharmaceutical manufacturing and R&D use only — not for direct administration
Packaging and handling
- Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
- Small quantities in sealed aluminium foil bags
- Palletised for air and sea freight; store dry, ventilated and protected from light
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Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.
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Request a QuoteReference: CAS 1038915-60-4 · PubChem CID 24958200