Vandetanib (CAS 443913-73-3)

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Vandetanib

CAS No. 443913-73-3
凡德他尼
Vandetanib structure
Chemical structure
CAS No.443913-73-3
Synonyms4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline
CategoryAnti-Cancer API / Anti-Cancer
Assay / Purity99%
Molecular FormulaC22H24BrFN4O2
Molecular Weight475.4
Melting Point—
Boiling Point—
Density—
Flash Point—
AppearanceOff-white to white solid powder

Application and positioning

Vandetanib is an inhibitor of the VEGFR2, EGFR and RET tyrosine kinases. It is used in oral tablets for unresectable or metastatic medullary thyroid cancer. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.

Quality and documentation

  • Batch-specific Certificate of Analysis issued by the manufacturing site
  • SDS/MSDS and specification sheet available on request
  • Residual solvents and elemental impurities statements discussed per project
  • For pharmaceutical manufacturing and R&D use only — not for direct administration

Packaging and handling

  • Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
  • Small quantities in sealed aluminium foil bags
  • Palletised for air and sea freight; store dry, ventilated and protected from light

Related products

Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.

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Reference: CAS 443913-73-3 · PubChem CID 3081361