Simeprevir Sodium (CAS 1241946-89-3)

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Simeprevir Sodium

CAS No. 1241946-89-3
西美瑞韦钠
Simeprevir Sodium structure
Chemical structure
CAS No.1241946-89-3
Synonyms8-Methyl-2-[4-(1-methyl ethyl) -2-thiazolyl]-4-quinolinyl] oxy]-5-methyl-4,14-dioxacyclopentadienyl [c] cyclopropyl [g] [1,6] diazocyclotetrazene-12a (1H) -sodium formamide salt
CategoryAnti-Hepatitis API / Anti-Hepatitis
Assay / Purity99%
Molecular FormulaC38H46N5NaO7S2
Molecular Weight771.9
Melting Point—
Boiling Point—
Density—
Flash Point—
AppearanceOff-white to white solid powder

Application and positioning

Simeprevir sodium is an NS3/4A protease inhibitor supplied as the sodium salt. It is used in oral capsules for chronic hepatitis C genotype 1 or 4, in interferon-free regimens with other direct-acting antivirals. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.

Quality and documentation

  • Batch-specific Certificate of Analysis issued by the manufacturing site
  • SDS/MSDS and specification sheet available on request
  • Residual solvents and elemental impurities statements discussed per project
  • For pharmaceutical manufacturing and R&D use only — not for direct administration

Packaging and handling

  • Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
  • Small quantities in sealed aluminium foil bags
  • Palletised for air and sea freight; store dry, ventilated and protected from light

Related products

Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.

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Reference: CAS 1241946-89-3 · PubChem CID 46866715