Tenofovir Alafenamide Fumarate (CAS 1392275-56-7)

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Tenofovir Alafenamide Fumarate

CAS No. 1392275-56-7
富马酸丙酚替诺福韦
Tenofovir Alafenamide Fumarate structure
Chemical structure
CAS No.1392275-56-7
SynonymsN-[(S)-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-L-alanine 1-methylethyl ester (2E)-2-butenedioate (2:1); GS 7340-03; GS 7340-03
CategoryAnti-Hepatitis API / Anti-Hepatitis
Assay / Purity99%
Molecular FormulaC46H62N12O14P2
Molecular Weight1069.0
Melting Point—
Boiling Point—
Density—
Flash Point—
AppearanceOff-white to white crystalline powder

Application and positioning

Tenofovir alafenamide fumarate is a phosphonamidate prodrug of tenofovir, supplied as the fumarate salt. It is used in oral tablets for chronic hepatitis B and HIV-1 infection, with lower plasma tenofovir exposure than tenofovir disoproxil. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.

Quality and documentation

  • Batch-specific Certificate of Analysis issued by the manufacturing site
  • SDS/MSDS and specification sheet available on request
  • Residual solvents and elemental impurities statements discussed per project
  • For pharmaceutical manufacturing and R&D use only — not for direct administration

Packaging and handling

  • Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
  • Small quantities in sealed aluminium foil bags
  • Palletised for air and sea freight; store dry, ventilated and protected from light

Related products

Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.

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Reference: CAS 1392275-56-7 · PubChem CID 71492247