Poziotinib (CAS 1092364-38-9)

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Poziotinib

CAS No. 1092364-38-9
波齐替尼
Poziotinib structure
Chemical structure
CAS No.1092364-38-9
Synonyms1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one
CategoryAnti-Cancer API / Anti-Cancer
Assay / Purity99%
Molecular FormulaC23H21Cl2FN4O3
Molecular Weight491.3
Melting Point—
Boiling Point—
Density—
Flash Point—
AppearanceOff-white to white solid powder

Application and positioning

Poziotinib is an irreversible pan-HER tyrosine kinase inhibitor developed for EGFR and HER2 exon 20 insertion mutations. It is an investigational oral agent studied in non-small cell lung cancer with exon 20 insertion mutations. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.

Quality and documentation

  • Batch-specific Certificate of Analysis issued by the manufacturing site
  • SDS/MSDS and specification sheet available on request
  • Residual solvents and elemental impurities statements discussed per project
  • For pharmaceutical manufacturing and R&D use only — not for direct administration

Packaging and handling

  • Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
  • Small quantities in sealed aluminium foil bags
  • Palletised for air and sea freight; store dry, ventilated and protected from light

Related products

Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.

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Reference: CAS 1092364-38-9 · PubChem CID 25127713