Axitinib (CAS 319460-85-0)

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Axitinib

CAS No. 319460-85-0
阿昔替尼
Axitinib structure
Chemical structure
CAS No.319460-85-0
SynonymsN-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide
CategoryAnti-Cancer API / Anti-Cancer
Assay / Purity99%
Molecular FormulaC22H18N4OS
Molecular Weight386.5
Melting Point—
Boiling Point—
Density—
Flash Point—
AppearanceOff-white to white solid powder

Application and positioning

Axitinib is a selective inhibitor of vascular endothelial growth factor receptors VEGFR-1, -2 and -3, which limits tumour angiogenesis. It is formulated into oral tablets for advanced renal cell carcinoma, frequently in combination with immune checkpoint inhibitors. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.

Quality and documentation

  • Batch-specific Certificate of Analysis issued by the manufacturing site
  • SDS/MSDS and specification sheet available on request
  • Residual solvents and elemental impurities statements discussed per project
  • For pharmaceutical manufacturing and R&D use only — not for direct administration

Packaging and handling

  • Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
  • Small quantities in sealed aluminium foil bags
  • Palletised for air and sea freight; store dry, ventilated and protected from light

Related products

Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.

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Reference: CAS 319460-85-0 · PubChem CID 6450551