Nintedanib Ethanesulfonate (CAS 656247-18-6)

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Nintedanib Ethanesulfonate

CAS No. 656247-18-6
乙磺酸尼达尼布
Nintedanib Ethanesulfonate structure
Chemical structure
CAS No.656247-18-6
Synonyms(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid methyl ester ethanesulfonate
CategoryAnti-Cancer API / Anti-Cancer
Assay / Purity99%
Molecular FormulaC33H39N5O7S
Molecular Weight649.8
Melting Point—
Boiling Point—
Density—
Flash Point—
AppearanceYellow to off-white solid powder

Application and positioning

Nintedanib ethanesulfonate is a triple-kinase inhibitor of VEGFR, FGFR and PDGFR, supplied as the ethanesulfonate salt. It is used in oral capsules for advanced lung adenocarcinoma and for idiopathic pulmonary fibrosis. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.

Quality and documentation

  • Batch-specific Certificate of Analysis issued by the manufacturing site
  • SDS/MSDS and specification sheet available on request
  • Residual solvents and elemental impurities statements discussed per project
  • For pharmaceutical manufacturing and R&D use only — not for direct administration

Packaging and handling

  • Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
  • Small quantities in sealed aluminium foil bags
  • Palletised for air and sea freight; store dry, ventilated and protected from light

Related products

Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.

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Reference: CAS 656247-18-6 · PubChem CID 135476717