9-Bromo-6,11-dihydro-8-hydroxy-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile (CAS 1256579-06-2)

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9-Bromo-6,11-dihydro-8-hydroxy-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile

CAS No. 1256579-06-2
9-溴-6,11-二氢-8-羟基-6,6-二甲基-11-氧代-5H-苯并[b]咔唑-3-甲腈
9-Bromo-6,11-dihydro-8-hydroxy-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile structure
Chemical structure
CAS No.1256579-06-2
Synonyms9-Bromo-6,11-dihydro-8-hydroxy-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile; sodium [(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] sulfate
CategoryPharmaceutical Intermediates / Anti-cancer
Assay / Purity99%
Molecular FormulaC19H13BrN2O2
Molecular Weight381.22
Melting Point—
Boiling Point—
Density—
Flash PointNot applicable (solid)
AppearanceOff-white to white solid powder

Application and positioning

A fully aromatic benzocarbazolone with a nitrile at C-3 and bromine at C-9 — a rigid, planar kinase-inhibitor core. The nitrile and the bromide are two independent handles; either can be used first. Laurand supplies it from audited Chinese producers in kilogram to multi-hundred-kilogram lots; process and regulatory documentation is coordinated case by case with the manufacturing site.

Quality and documentation

  • Batch-specific Certificate of Analysis with HPLC purity and a full impurity profile
  • Chiral purity by chiral HPLC where the molecule carries defined stereocentres
  • Residual solvent data against ICH Q3C and elemental impurity data against ICH Q3D on request
  • Structure confirmation by NMR and MS on first shipments
  • SDS in the language of your market, with GHS classification for the destination

Packaging and handling

  • 1 kg, 5 kg and 25 kg fibre drums with inner PE liner; amber glass bottles for gram quantities
  • Sealed, dry and protected from light; cold-chain arrangement discussed per product where the intermediate requires it
  • Store at ambient temperature in a dry warehouse, away from oxidising agents and moisture

Related products

Values marked (predicted) are calculated estimates; the rest are published literature or supplier data. Where a property has no published value we leave it blank rather than estimate it. The specification of the delivered lot is confirmed with the quotation.

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Reference: CAS 1256579-06-2 · PubChem CID 54578769