N-Methyl-1-(methylthio)-2-nitroethenamine (CAS 61832-41-5)

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N-Methyl-1-(methylthio)-2-nitroethenamine

CAS No. 61832-41-5
N-Methyl-1-(methylthio)-2-nitroethenamine structure
Chemical structure
CAS No.61832-41-5
SynonymsRanitidine intermediate; Nizatidine fragment; (E)-N-methyl-1-methylsulfanyl-2-nitroethenamine
CategoryPharmaceutical Intermediates / GI & respiratory
Assay / Purity98%
Molecular FormulaC4H8N2O2S
Molecular Weight148.19
Melting Point—
Boiling Point—
Density—
Flash PointNot applicable (solid)
AppearanceWhite to off-white powder

Application and positioning

The nitroethenamine building block for the H2-antagonist family — ranitidine and nizatidine routes condense it with the furan side chain in the final assembly step. Supplied as E-isomer dominant crystalline solid; packaged under nitrogen for moisture-sensitive handling. Laurand supplies it from audited Chinese producers in kilogram to multi-hundred-kilogram lots; process and regulatory documentation is coordinated case by case with the manufacturing site.

Quality and documentation

  • Batch-specific Certificate of Analysis with HPLC purity and a full impurity profile
  • Chiral purity by chiral HPLC where the molecule carries defined stereocentres
  • Residual solvent data against ICH Q3C and elemental impurity data against ICH Q3D on request
  • Structure confirmation by NMR and MS on first shipments
  • SDS in the language of your market, with GHS classification for the destination

Packaging and handling

  • 1 kg, 5 kg and 25 kg fibre drums with inner PE liner; amber glass bottles for gram quantities
  • Sealed, dry and protected from light; cold-chain arrangement discussed per product where the intermediate requires it
  • Store at ambient temperature in a dry warehouse, away from oxidising agents and moisture

Related products

Values marked (predicted) are calculated estimates; the rest are published literature or supplier data. Where a property has no published value we leave it blank rather than estimate it. The specification of the delivered lot is confirmed with the quotation.

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Reference: CAS 61832-41-5 · PubChem CID 3035401