Galunisertib (CAS 700874-72-2)
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Galunisertib
CAS No. 700874-72-2
LY 2157299
Chemical structure
| CAS No. | 700874-72-2 |
|---|---|
| Synonyms | 4-(2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo-[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide |
| Category | Anti-Cancer API / Anti-Cancer |
| Assay / Purity | 99% |
| Molecular Formula | C22H19N5O |
| Molecular Weight | 369.4 |
| Melting Point | — |
| Boiling Point | — |
| Density | — |
| Flash Point | — |
| Appearance | Off-white to white solid powder |
Application and positioning
Galunisertib is a selective inhibitor of the TGF-beta receptor type I (ALK5) kinase that blocks SMAD2/3 signalling. It is an investigational oral agent studied in myelodysplastic syndromes, hepatocellular carcinoma and pancreatic cancer. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.
Quality and documentation
- Batch-specific Certificate of Analysis issued by the manufacturing site
- SDS/MSDS and specification sheet available on request
- Residual solvents and elemental impurities statements discussed per project
- For pharmaceutical manufacturing and R&D use only — not for direct administration
Packaging and handling
- Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
- Small quantities in sealed aluminium foil bags
- Palletised for air and sea freight; store dry, ventilated and protected from light
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Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.
Interested in this product?
Contact us for price, COA, MSDS and lead time — custom synthesis available.
Request a QuoteReference: CAS 700874-72-2 · PubChem CID 10090485