Vemurafenib (CAS 918504-65-1)
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Vemurafenib
CAS No. 918504-65-1
维莫非尼
Chemical structure
| CAS No. | 918504-65-1 |
|---|---|
| Synonyms | PLX 4032; N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide |
| Category | Anti-Cancer API / Anti-Cancer |
| Assay / Purity | 99% |
| Molecular Formula | C23H18ClF2N3O3S |
| Molecular Weight | 489.9 |
| Melting Point | — |
| Boiling Point | — |
| Density | — |
| Flash Point | — |
| Appearance | Off-white to white solid powder |
Application and positioning
Vemurafenib is a selective inhibitor of the BRAF V600E mutant kinase. It is used in oral tablets for BRAF V600E-positive unresectable or metastatic melanoma. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.
Quality and documentation
- Batch-specific Certificate of Analysis issued by the manufacturing site
- SDS/MSDS and specification sheet available on request
- Residual solvents and elemental impurities statements discussed per project
- For pharmaceutical manufacturing and R&D use only — not for direct administration
Packaging and handling
- Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
- Small quantities in sealed aluminium foil bags
- Palletised for air and sea freight; store dry, ventilated and protected from light
Related products
- Acalabrutinib, ACP-196 (CAS 1420477-60-6)
- Afatinib Dimaleate (CAS 850140-73-7)
- Alectinib Hydrochloride (CAS 1256589-74-8)
- Axitinib (CAS 319460-85-0)
- 5-Bromo-1H-pyrrolo[2,3-b]pyridine (CAS 183208-35-7)
Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.
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Request a QuoteReference: CAS 918504-65-1 · PubChem CID 42611257