Regorafenib Hydrate (CAS 1019206-88-2)
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Regorafenib Hydrate
CAS No. 1019206-88-2
瑞戈非尼一水合物
Chemical structure
| CAS No. | 1019206-88-2 |
|---|---|
| Synonyms | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrate |
| Category | Anti-Cancer API / Anti-Cancer |
| Assay / Purity | 99% |
| Molecular Formula | C21H17ClF4N4O4 |
| Molecular Weight | 500.8 |
| Melting Point | — |
| Boiling Point | — |
| Density | — |
| Flash Point | — |
| Appearance | White to slightly pink or lightly brownish crystalline powder |
Application and positioning
Regorafenib hydrate is a multi-kinase inhibitor of VEGFR1-3, TIE2, PDGFR, FGFR, KIT and RET, supplied as the monohydrate. It is used in oral tablets for metastatic colorectal cancer, gastrointestinal stromal tumours and hepatocellular carcinoma. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.
Quality and documentation
- Batch-specific Certificate of Analysis issued by the manufacturing site
- SDS/MSDS and specification sheet available on request
- Residual solvents and elemental impurities statements discussed per project
- For pharmaceutical manufacturing and R&D use only — not for direct administration
Packaging and handling
- Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
- Small quantities in sealed aluminium foil bags
- Palletised for air and sea freight; store dry, ventilated and protected from light
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- Vandetanib (CAS 443913-73-3)
- Veliparib (CAS 912444-00-9)
- 4-(4-Amino-3-chlorophenoxy)-N-methylpicolinamide (CAS 284462-44-8)
Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.
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Request a QuoteReference: CAS 1019206-88-2 · PubChem CID 24768591