Upadacitinib (CAS 1310726-60-3)

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Upadacitinib

CAS No. 1310726-60-3
乌帕替尼
Upadacitinib structure
Chemical structure
CAS No.1310726-60-3
Synonyms(3S, 4R)-3-Ethyl-4-(3H-imidazo [1,2-a] pyrrole [2,3-e] pyrazine-8-yl)-N-(2,2,2-trifluoroethyl) pyrrolidine-1-formamide; ABT-494
CategoryAnti-Rheumatism API / Anti-Rheumatism
Assay / Purity99%
Molecular FormulaC17H19F3N6O
Molecular Weight380.4
Melting Point—
Boiling Point—
Density—
Flash Point—
AppearanceOff-white to white solid powder

Application and positioning

Upadacitinib is a JAK1-selective inhibitor supplied as the free base. It is used in oral extended-release tablets for rheumatoid arthritis, atopic dermatitis, psoriatic arthritis and axial spondyloarthritis. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.

Quality and documentation

  • Batch-specific Certificate of Analysis issued by the manufacturing site
  • SDS/MSDS and specification sheet available on request
  • Residual solvents and elemental impurities statements discussed per project
  • For pharmaceutical manufacturing and R&D use only — not for direct administration

Packaging and handling

  • Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
  • Small quantities in sealed aluminium foil bags
  • Palletised for air and sea freight; store dry, ventilated and protected from light

Related products

Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.

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Reference: CAS 1310726-60-3 · PubChem CID 58557659