Methotrexate (CAS 59-05-2)
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Methotrexate
CAS No. 59-05-2
甲氨蝶呤
Chemical structure
| CAS No. | 59-05-2 |
|---|---|
| Synonyms | (+)-Amethopterin; (+)-4-Amino-10-methylfolic acid; N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamic acid |
| Category | Anti-Rheumatism API / Anti-Rheumatism |
| Assay / Purity | 99% |
| Molecular Formula | C20H22N8O5 |
| Molecular Weight | 454.4 |
| Melting Point | — |
| Boiling Point | — |
| Density | — |
| Flash Point | — |
| Appearance | Yellow crystalline powder |
Application and positioning
Methotrexate is a folate antagonist that inhibits dihydrofolate reductase, supplied as the free acid. It is used in low-dose oral and injectable forms for rheumatoid arthritis and psoriasis, and at higher doses in oncology. Laurand supplies it from audited Chinese production partners for pharmaceutical manufacturing and process development.
Quality and documentation
- Batch-specific Certificate of Analysis issued by the manufacturing site
- SDS/MSDS and specification sheet available on request
- Residual solvents and elemental impurities statements discussed per project
- For pharmaceutical manufacturing and R&D use only — not for direct administration
Packaging and handling
- Packed in double polyethylene-lined fibre drums; pack size confirmed at quotation
- Small quantities in sealed aluminium foil bags
- Palletised for air and sea freight; store dry, ventilated and protected from light
Related products
- Upadacitinib (CAS 1310726-60-3)
- Baricitinib (CAS 1187594-09-7)
- Tofacitinib Citrate (CAS 540737-29-9)
- N-(4-Aminobenzoyl)-L-glutamic acid (CAS 4271-30-1)
Specifications shown are indicative. The final specification and documentation package are confirmed with the quotation.
Interested in this product?
Contact us for price, COA, MSDS and lead time — custom synthesis available.
Request a QuoteReference: CAS 59-05-2 · PubChem CID 126941