5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione (CAS 830346-48-0)

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5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione

CAS No. 830346-48-0
5-溴-1-[2-氟-6-(三氟甲基)苄基]-6-甲基嘧啶-2,4(1H,3H)-二酮
5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione structure
Chemical structure
CAS No.830346-48-0
Synonyms5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione; 5-bromo-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methylpyrimidine-2,4-dione
CategoryPharmaceutical Intermediates / Anti-cancer
Assay / Purity99%
Molecular FormulaC13H9BrF4N2O2
Molecular Weight381.12
Melting Point—
Boiling Point—
Density—
Flash PointNot applicable (solid)
AppearanceWhite to off-white powder

Application and positioning

A 6-methyluracil with a 2-fluoro-6-(trifluoromethyl)benzyl at N-1 and bromine at C-5. The benzyl group carries the activity in this series; the 5-bromo is the point for further substitution. Laurand supplies it from audited Chinese producers in kilogram to multi-hundred-kilogram lots; process and regulatory documentation is coordinated case by case with the manufacturing site.

Quality and documentation

  • Batch-specific Certificate of Analysis with HPLC purity and a full impurity profile
  • Chiral purity by chiral HPLC where the molecule carries defined stereocentres
  • Residual solvent data against ICH Q3C and elemental impurity data against ICH Q3D on request
  • Structure confirmation by NMR and MS on first shipments
  • SDS in the language of your market, with GHS classification for the destination

Packaging and handling

  • 1 kg, 5 kg and 25 kg fibre drums with inner PE liner; amber glass bottles for gram quantities
  • Sealed, dry and protected from light; cold-chain arrangement discussed per product where the intermediate requires it
  • Store at ambient temperature in a dry warehouse, away from oxidising agents and moisture

Related products

Values marked (predicted) are calculated estimates; the rest are published literature or supplier data. Where a property has no published value we leave it blank rather than estimate it. The specification of the delivered lot is confirmed with the quotation.

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Reference: CAS 830346-48-0 · PubChem CID 11682386